Witkiewicz, MD is Director of the Advanced Tissue Imaging Resource and a physician-scientist at Roswell Park Comprehensive Cancer Center. Her work focuses on defining the molecular and cellular mechanisms that drive pancreatic cancer development, progression, and therapeutic response. Dr. Witkiewicz has been a leader in the development and characterization of patient-derived pancreatic cancer models and has extensively studied KRAS-driven disease, tumor heterogeneity, and interactions between cancer cells and the tumor microenvironment. Through close integration of pathology, genomics, and translational science, her research seeks to identify biomarkers of response and develop more effective treatment strategies for patients with pancreatic cancer.