Dr. Colin Weekes is a medical oncologist specializing in gastrointestinal malignancies in the Tucker Gosnell Center for Gastrointestinal Cancers at the Massachusetts General Hospital Cancer Center, where he is also the Director of Medical Oncology Research for Pancreatic Cancer. He is the inaugural incumbent Christopher D. Horner Endowed Chair in Pancreatic Cancer. He is an Associate Professor at the Harvard Medical School. Dr. Weekes’ translational research career has focused on early drug development in gastrointestinal malignancies with a focus on pancreas cancer. He has worked to translate laboratory findings into clinical strategies to improve the outcomes for patients with pancreas cancer. Much of his translational research has led to the development of strategies to target various components of the tumor microenvironment and the consequent cellular signal transduction as a therapeutic strategy. In addition, Dr. Weekes has a longstanding interest in the equitable participation of patients of diverse backgrounds in clinical trials.